Covaris Ultrasonicators

 

Covaris S220 Ultrasonicator

 

 

The S220 Focused-ultrasonicator is a versatile, high power system engineered for pre-analytical sample processing with Covaris’ patented Adaptive Focused Acoustics (AFA). The versatility of the S220 Focused-ultrasonicator makes it possible to bring the advantages of AFA to numerous biological and chemical applications including, DNA, RNA, and chromatin shearing, tissue homogenization, cell lysis, compound dissolution, and particle micronization.

 

Compatible tubes: AFA tubes

 


 

Covaris E220 High-throughput Ultrasonicator

 

 

 

High-throughput sonication is available with Covaris E220 to process 1 – 96 samples in 96-well plate, fragment size range between 150 bp and 5 kb using their AFA technology.

 

Compatible tubes: microTUBES, miniTUBES, 96 microTUBE Plates and 8 microTUBE Strip

 


 

Digilab HydroShear

 

 

The HydroShear is used for fragmenting DNA to sizes larger than 1KB. HydroShear offers the simplest, most reproducible, and most controllable method available for generating random DNA fragments. This device uses hydrodynamic shearing forces to fragment DNA strands. HydroShear can handle any source of DNA at any concentration in volumes as small as 40μl. DNA fragments can be sheared within a two-fold size distribution (e.g. if the target size is 2kb, the HydroShear can be calibrated to produce a distribution centered on 2kb with 90% of the DNA falling between 1.3kb and 2.6kb. It is the best system for making long DNA fragments for single molecule sequencing such as PacBio Sequel.